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What differences are detected by superiority trials or ruled out by noninferiority trials? A cross-sectional study on a random sample of two-hundred two-arms parallel group randomized clinical trials

  • Angèle Gayet-Ageron1Email author,
  • Thomas Agoritsas1,
  • Christophe Combescure1,
  • Krisztina Bagamery1,
  • Delphine S Courvoisier1 and
  • Thomas V Perneger1
BMC Medical Research Methodology201010:93

DOI: 10.1186/1471-2288-10-93

Received: 26 April 2010

Accepted: 15 October 2010

Published: 15 October 2010

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
26 Apr 2010 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
26 Apr 2010 Author responded Author comments - Angèle Gayet-Ageron
Resubmission - Version 3
26 Apr 2010 Submitted Manuscript version 3
20 Jul 2010 Reviewed Reviewer Report - Vance Berger
6 Sep 2010 Reviewed Reviewer Report - Yuliya Lokhnygina
27 Sep 2010 Author responded Author comments - Angèle Gayet-Ageron
Resubmission - Version 4
27 Sep 2010 Submitted Manuscript version 4
Resubmission - Version 5
Submitted Manuscript version 5
7 Oct 2010 Reviewed Reviewer Report - Vance Berger
12 Oct 2010 Reviewed Reviewer Report - Yuliya Lokhnygina
15 Oct 2010 Author responded Author comments - Angèle Gayet-Ageron
Resubmission - Version 6
15 Oct 2010 Submitted Manuscript version 6
Publishing
15 Oct 2010 Editorially accepted
15 Oct 2010 Article published 10.1186/1471-2288-10-93

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Division of Clinical Epidemiology, University Hospitals of Geneva and Faculty of Medicine, University of Geneva

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