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Table 2 Requirements for Paired Availablity Design

From: The Paired Availability Design for Historical Controls

Requirement

Specific Criteria

Stable population

1.

Hospital serves one geographic area or

  

is military medical center

 

2.

No in- or out- migration

 

3.

Eligibility criteria constant over time

 

4.

No underlying change in prognosis

  

over time

Stable treatment

1.

Other patient management constant

  

over time

Stable evaluation

1.

Evaluation criteria constant over time

Stable preference

1.

No publicized credible reports

 

2.

No direct-to-consumer advertising

Effect of the intervention on outcome does

1.

Effect of intervention does not depend

not change with a change in availability

 

on when the intervention was given

(only applicable when some in "before"

 

during the course of disease

group receive intervention)

2.

No learning curve for the intervention