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Table 2 Potential applications of a national asthma database.

From: A methodology to establish a database to study gene environment interactions for childhood asthma

Potential application Resource
Identification of genetically susceptible individuals for pharmacogenetic studies DNA
Identification of genetically susceptible individuals for environmental modification studies DNA
Characterisation of patterns of inhaled environmental hazards in children with asthma Questionnaire and longitudinal component
Validate a system to score asthma severity All data
Explore gene-environment interactions for subgroups, eg severe asthma, non-atopic asthma Subgroups
Audit standard of care between centres Management + CACQ
Identify associations between gene-environment interactions and natural history Longitudinal study
Confirm associations seen in secondary care study Primary care study