Figure 2
From: Can we rely on the best trial? A comparison of individual trials and systematic reviews
Estimates of effect for the index (highest weighted) trials compared to the meta-analysis (larger circles have higher weight within the review): A. Relative Risks (RR) where the index trial is more than 50% of the weight (A1) and less than 50% (A2); B. Weighted Mean Differences where the index trial is more than 50% of the weight (B1) and less than 50% (B2) - note: for the 4 trials and meta-analyses with WMDs more than 10 (or -10) we rescaled to fit.