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Table 2 Agreement on statistical significance between the overall results of the systematic review and the most precise single trial.1

From: Can we rely on the best trial? A comparison of individual trials and systematic reviews

 

Meta-analysis or single trial

Large Trial

P < 0.05

P > 0.05

P < 0.05

55 (including 14 single trial reviews)

5

p > 0.05

31

70 (including 15 single trial reviews)

  1. 1 Six single trial reviews are excluded due to insufficient data