Skip to main content

Advertisement

Table 4 Different effect model of the recurrent MI events in the LIPID study

From: Semi-parametric risk prediction models for recurrent cardiovascular events in the LIPID study

Risk factor First MI event Second MI event Wald test
  HR 95% CI P-value HR 95% CI P-value  
Age (year) 1.02 1.01 - 1.03 <0.001 1.04 1.01 - 1.06 0.007 0.14
Smoking status        
   Non-smoker 1.0    1.0    
   Current smoker 1.49 1.20 - 1.85 <0.001 1.71 0.94 - 3.12 0.079 0.63
Total cholesterol 1.18 1.08 - 1.28 <0.001 1.34 1.08 - 1.66 0.007 0.21
HDL cholesterol 0.41 0.29 - 0.59 <0.001 0.17 0.06 - 0.47 0.001 0.076
Qualifying event for ACS        
   Unstable angina 1.0    1.0    
   Single MI 1.27 1.06 - 1.53 0.011 1.44 0.81 - 2.54 0.21 0.66
   Multiple MI 1.92 1.54 - 2.40 <0.001 2.46 1.34 - 4.54 0.004 0.39
Revascularization        
   Never 1.0    1.0    
   Before ACS 1.54 1.23 - 1.92 <0.001 2.02 1.10 - 3.74 0.024 0.34
   Since ACS 0.70 0.58 - 0.85 <0.001 0.65 0.36 - 1.16 0.14 0.76
History of stroke        
   No 1.0    1.0    
   Yes 1.50 1.12 - 2.00 0.006 1.31 0.57 - 3.04 0.53 0.75
Diabetes mellitus        
   No 1.0    1.0    
   Yes 1.40 1.12 - 1.75 0.003 1.14 0.58 - 2.23 0.70 0.53
Angina grade        
   CCVS < III 1.0    1.0    
   CCVS ≥ III 1.44 1.16 - 1.80 0.001 1.48 0.83 - 2.65 0.18 0.91
Treatment        
   Placebo 1.0    1.0    
   Pravastatin 0.72 0.62 - 0.83 <0.001 0.66 0.43 - 0.99 0.047 0.67
  1. † P-value for Wald test. ACS = Acute Coronary Syndrome; CCVS = Canadian Cardiovascular Society Class of angina; HDL = High Density Lipoprotein; MI = Myocardial Infarction.