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Table 1 Outcomes for a single-test cancer screening trial

From: Estimates of sensitivity and specificity can be biased when reporting the results of the second test in a screening trial conducted in series

True Disease Status

Test 2 Result

Elective Procedure

Observed Disease Status

+

+

--

+

+

-

Yes

+

+

-

No

-

-

+

Yes

-

-

+

No

-

-

-

Yes

-

-

-

No

-

  1. A double dash indicates an event that will not occur under the assumptions of our model. Cases misclassified as non-cases.