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Table 3 Observed disease status and Test 2 results in a single test trial design

From: Estimates of sensitivity and specificity can be biased when reporting the results of the second test in a screening trial conducted in series

   Observed Disease Status
   + -
Test 2 + p D TP(2) (1 - pD)FP(2)
  - p D p E FN(2) p D (1 - p E )FN(2)+(1 - p D )TN(2)