Skip to main content

Advertisement

Table 2 Match between identified models with requirements of HTA programme

From: A systematic review of models to predict recruitment to multicentre clinical trials

Paper Model Type Simplicity Can adapt to epidemiological changes Can adapt to environmental changes Centre Recruitment Could inform commissioning Decisions
Carter (2004) Simulation using Poisson distribution Y P Y Y Y
Carter (2005) Unconditional Y Y N N Y
  Conditional Y Y Y Y Y
  Simulation using Poisson distribution Y P Y Y Y
  Simulation using Poisson distribution with average recruitment rates (λ) varied according to a uniform distribution Y P Y Y Y
Anisimov (2007) Poisson process with recruitment rates (λ) viewed as a sample from a gamma distribution N Y Y N P
Moussa (1984) Conditional Y Y Y N Y
Williford (1987) Poisson N Y Y N N
  Negative binomial (Poisson process with recruitment rates (λ) viewed as a sample from a gamma distribution) N Y Y Y N
  Lees contagious poisson N Y Y Y N
  Bayesian - prior distribution is possion-gamma, posterior is gamma N Y Y N N
Gajewski (2007) Bayesian - prior distribution is the inverse gamma, likelihood is the exponential distribution, posterior distribution is the inverse gamma N Y Y P Y
Abbas (2007) Markov N P Y N Y
Hadich (2001) Time series N P N N N
  1. Y = Criterion met
  2. N = Criterion not met
  3. P = Posssibly: Criteron could be met, dependent on circumstance