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Table 1 Criteria for exclusion from exercise testing at field laboratories and for stopping tests.

From: Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia

Exclusion Criteria for testing at field laboratories
• Resting blood pressure >200 mmHg Systolic, and or >110 mmHg Diastolic
• Acute systemic infection (discuss with medical officer)
• AMS requiring treatment with acetazolamide, dexamethasone or nifedipine
• Acute chest pain
• New Arrhythmias or ECG changes
• Resting Arterial Oxygen Saturations <90% at sea level; <85% Kathmandu, <80% Namche <75% Pheriche, <70% at Everest Base Camp
Criteria for stopping test
• Excessive rise in blood pressure:
    >250 mmHg Systolic; >115 mmHg Diastolic
• Drop in systolic blood pressure of >10 mmHg from baseline, with other indications of ischaemia (see below)
   • >2 mm ST depression or >1 mm ST elevation
   • Onset of angina or angina-like symptoms
   • Onset of new arrhythmia other than ventricular ectopics
• Nervous system symptoms - ataxia, dizziness or near syncope
• Subject requests termination of test