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Table 3 Adjusted hazard ratios (HR, 95% CI) for quartiles of PCS-12 and MCS-12 associated with all-cause mortality.

From: Self-perceived quality of life predicts mortality risk better than a multi-biomarker panel, but the combination of both does best

  PCS-12 in quartiles
(Ref.: highest quartile) min/43.6 43.6/47.5 47.5/50.1 p for Trend
Model 1: adjusted for age & gender 1.75 (1.31; 2.33) * 1.12 (0.81; 1.55) 1.07 (0.77; 1.49) < 0.001
Model 1 + socio-demographic factors a 1.63 (1.22; 2.17) * 1.08 (0.78; 1.50) 1.03 (0.74; 1.44) < 0.001
Model 1 + behavioral factors b 1.78 (1.33; 2.40) * 1.13 (0.81; 1.58) 1.08 (0.77; 1.52) < 0.001
Model 1 + comorbidities c 1.60 (1.19; 2.14) * 1.08 (0.77; 1.49) 1.03 (0.74; 1.45) < 0.001
Model 1 + biomarker panel d 1.64 (1.19; 2.27) * 1.08 (0.75; 1.55) 1.08 (0.75; 1.56) < 0.001
  MCS-12 in quartiles
  min/40.8 40.8/44.4 44.4/48.0 p for Trend
Model 1: adjusted for age & gender 0.97 (0.75; 1.24) 0.91 (0.70; 1.17) 0.84 (0.65; 1.08) 0.759
Model 1 + socio-demographic factors a 0.98 (0.76; 1.26) 0.98 (0.75; 1.26) 0.87 (0.68; 1.12) 0.944
Model 1 + behavioral factors b 1.06 (0.82; 1.37) 0.95 (0.73; 1.23) 0.88 (0.68; 1.13) 0.707
Model 1 + comorbidities c 0.96 (0.74; 1.23) 0.92 (0.71; 1.19) 0.87 (0.68; 1.12) 0.689
Model 1 + biomarker panel d 0.97 (0.74; 1.28) 0.93 (0.70; 1.23) 0.85 (0.65; 1.12) 0.840
  1. * p < 0.05; HR, hazard ratio; 95% CI, 95% confidence interval; PCS-12, Physical Component Summary; MCS-12, Mental Component Summary.
  2. a, HR adjusted for age, gender, civil status, educational level, occupational status, and equalized income.
  3. b, HR adjusted for age, gender, smoking status, alcohol consumption, physical activity, food consumption, and waist circumference.
  4. c, HR adjusted for age, gender, previous history of hypertension, myocardial infarction, stroke, and diabetes mellitus.
  5. d, HR adjusted for age, gender, high sensitive C-reactive protein, fibrinogen, glycated hemoglobin, total cholesterol, triglycerides, glomerular filtration rate, albumin, gamma glutamyltransferase, thyrotropin, and insulin-like growth factor-I.