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Table 3 Adjusted hazard ratios (HR, 95% CI) for quartiles of PCS-12 and MCS-12 associated with all-cause mortality.

From: Self-perceived quality of life predicts mortality risk better than a multi-biomarker panel, but the combination of both does best

 

PCS-12 in quartiles

(Ref.: highest quartile)

min/43.6

43.6/47.5

47.5/50.1

p for Trend

Model 1: adjusted for age & gender

1.75 (1.31; 2.33) *

1.12 (0.81; 1.55)

1.07 (0.77; 1.49)

< 0.001

Model 1 + socio-demographic factors a

1.63 (1.22; 2.17) *

1.08 (0.78; 1.50)

1.03 (0.74; 1.44)

< 0.001

Model 1 + behavioral factors b

1.78 (1.33; 2.40) *

1.13 (0.81; 1.58)

1.08 (0.77; 1.52)

< 0.001

Model 1 + comorbidities c

1.60 (1.19; 2.14) *

1.08 (0.77; 1.49)

1.03 (0.74; 1.45)

< 0.001

Model 1 + biomarker panel d

1.64 (1.19; 2.27) *

1.08 (0.75; 1.55)

1.08 (0.75; 1.56)

< 0.001

 

MCS-12 in quartiles

 

min/40.8

40.8/44.4

44.4/48.0

p for Trend

Model 1: adjusted for age & gender

0.97 (0.75; 1.24)

0.91 (0.70; 1.17)

0.84 (0.65; 1.08)

0.759

Model 1 + socio-demographic factors a

0.98 (0.76; 1.26)

0.98 (0.75; 1.26)

0.87 (0.68; 1.12)

0.944

Model 1 + behavioral factors b

1.06 (0.82; 1.37)

0.95 (0.73; 1.23)

0.88 (0.68; 1.13)

0.707

Model 1 + comorbidities c

0.96 (0.74; 1.23)

0.92 (0.71; 1.19)

0.87 (0.68; 1.12)

0.689

Model 1 + biomarker panel d

0.97 (0.74; 1.28)

0.93 (0.70; 1.23)

0.85 (0.65; 1.12)

0.840

  1. * p < 0.05; HR, hazard ratio; 95% CI, 95% confidence interval; PCS-12, Physical Component Summary; MCS-12, Mental Component Summary.
  2. a, HR adjusted for age, gender, civil status, educational level, occupational status, and equalized income.
  3. b, HR adjusted for age, gender, smoking status, alcohol consumption, physical activity, food consumption, and waist circumference.
  4. c, HR adjusted for age, gender, previous history of hypertension, myocardial infarction, stroke, and diabetes mellitus.
  5. d, HR adjusted for age, gender, high sensitive C-reactive protein, fibrinogen, glycated hemoglobin, total cholesterol, triglycerides, glomerular filtration rate, albumin, gamma glutamyltransferase, thyrotropin, and insulin-like growth factor-I.