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Table 2 Reporting quality of key methodological items
| Items | 2008(n = 107) | 1998(n = 99) | 2008 VS 1998 | |
|---|---|---|---|---|
| n(%) | n(%) | RR [95%CI] | Pvalue | |
| Sequence generation | ||||
| adequate reporting | 23(22%) | 10(10%) | 2.44[1.09,5.42] | < 0.05 |
| partial reporting | 58(54%) | 25(25%) | < 0.05 | |
| no reporting | 26(24%) | 64(75%) | < 0.05 | |
| *adequate + partial reporting | 81(76%) | 35(35%) | 5.70[3.11,10.42] | < 0.05 |
| Allocation concealment | ||||
| adequate reporting | 6(6%) | 3(3%) | 1.90[0.46,7.82] | 0.89 |
| partial reporting | 56(52%) | 22(22%) | < 0.05 | |
| no reporting | 45(42%) | 74(75%) | < 0.05 | |
| *adequate + partial reporting | 62(58%) | 25(25%) | 4.08 [2.25, 7.39] | < 0.05 |
| Blinding | ||||
| adequate reporting | 24(22%) | 22(22%) | 1.01[0.52,1.95] | 0.97 |
| partial reporting | 38(36%) | 30(30%) | 0.43 | |
| no reporting | 45(42%) | 47(47%) | 0.43 | |
| *adequate + partial reporting | 62(58%) | 52(53%) | 1.25 [0.72, 2.16] | 0.43 |
| Sample size calculation | ||||
| adequate reporting | 28(26%) | 13(13%) | 2.34[1.14,4.84] | < 0.05 |
| partial reporting | 55(52%) | 34(34%) | < 0.05 | |
| no reporting | 24(22%) | 52(53%) | < 0.05 | |
| *adequate + partial reporting | 83(78%) | 47(47%) | 3.83 [2.10, 6.98] | < 0.05 |
| Incomplete outecome data addressed | ||||
| adequate reporting | 20(19%) | 12(12%) | 1.67[0.77,3.62] | 0.2 |
| partial reporting | 32(30%) | 22(22%) | 0.21 | |
| no reporting | 55(51%) | 65(66%) | < 0.05 | |
| *adequate + partial reporting | 52(49%) | 34(34%) | 1.81[1.03,3.17] | < 0.05 |
| Intention-to-treat analysis | ||||
| adequate reporting | 49(46%) | 30(30%) | 1.94[1.10,3.45] | < 0.05 |
| partial reporting | 25(23%) | 12(12%) | < 0.05 | |
| no reporting | 33(31%) | 57(58%) | < 0.05 | |
| *adequate + partial reporting | 74(69%) | 42(42%) | 3.04 [1.72, 5.39] | < 0.05 |
| Free of selective reporting | ||||
| adequate reporting | 34(32%) | 20(20%) | 1.84[0.97,3.48] | 0.06 |
| partial reporting | 23(21%) | 23(23%) | 0.76 | |
| no reporting | 50(47%) | 56(57%) | 0.16 | |
| *adequate + partial reporting | 57(53%) | 43(43%) | 1.48[0.86,2.57] | 0.16 |
