Advertisement
Table 3 Methodological issues that were addressed numerically with frequencies of participants or other statistical methods
From: Questions asked and answered in pilot and feasibility randomized controlled trials
| Issue | Drug (n = 28) | Non-drug (n = 22) | |
|---|---|---|---|
| Recruitment | none | 21 (75%) | 9 (41%) |
| brief coverage | 5 (18%) | 4 (18%) | |
| detailed coverage | 1 (4%) | 3 (14%) | |
| tabulated/figure | 1 (4%) | 6 (27%) | |
| Retention | none | 16 (57%) | 9 (41%) |
| brief coverage | 6 (21%) | 7 (32%) | |
| detailed coverage | 0 | 0 | |
| tabulated/figure | 6 (21%) | 6 (27%) | |
| Compliance/adherence with the intervention | none | 14 (50%) | 10 (46%) |
| brief coverage | 7 (25%) | 7 (32%) | |
| detailed coverage | 5 (18%) | 1 (5%) | |
| tabulated/figure | 2 (7%) | 4 (18%) | |
| Blinding procedures | brief coverage | 2 (7%) | 1 (5%) |
| Acceptability of the intervention to participants | brief coverage | 1 (4%) | 1 (5%) |
| detailed coverage | 0 | 1 (5%) | |
| tabulated/figure | 0 | 2(9%) | |
| Other aspects of the intervention | brief coverage | 1 (4%) | 2 (9%) |
| detailed coverage | 0 | 1 (5%) | |
| tabulated/figure | 0 | 2 (9%) | |
| Outcome assessment | brief coverage | 1 (4%) | 4 (18%) |
| detailed coverage | 1 (4%) | 0 | |
| tabulated/figure | 0 | 1 (5%) | |
| Randomization procedure | brief coverage | 0 | 2 (9%) |
| detailed coverage | 0 | 1 (5%) | |
| Acceptability of trial procedures | brief coverage | 1 (4%) | 0 |
| detailed coverage | 0 | 3 (14%) | |
| Logistics of multi-centre procedures | detailed coverage | 0 | 1 (4%) |
