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Table 1 Description of the observed and the simulated data sets for breast cancer and malignant melanoma patients

From: Imputation of missing values of tumour stage in population-based cancer registration

  

Breast cancer data set

Malignant melanoma data set

  

Observed

Simulated*

Observed

Simulated*

Number of cases

 

21,428

17,162

5,520

1,685

Sex (in %)

Female

100

100

45.8

45.1

 

Male

0

0

54.2

54.9

Age

Median

(1st and 3rd Quartile)

62.0

(53.0; 71.0)

61.0

(52.0; 69.0)

61.0

(45.0; 70.2)

59.0

(43.0; 68.0)

T-stage (in %)

1

47.3

49.2

36.9

36.9

 

2

34.0

34.3

11.8

12.4

 

3

5.5

5.1

8.0

7.6

 

4

7.3

5.7

4.7

4.4

 

Unknown

6.0

5.7

38.6

38.7

N-stage (in %)

0

53.4

55.1

29.5

32.5

 

1

25.4

25.2

1.7

1.4

 

2

6.1

5.9

0.6

0.4

 

3

3.7

3.5

0.2

0.1

 

Unknown

11.4

10.3

67.9

65.6

M-stage (in %)

0

77.9

80.8

31.0

33.5

 

1

5.6

3.7

2.2

0.7

 

Unknown

16.5

15.4

66.8

65.8

UICC-stage (in %)

I

32.0

29.7

23.9

7.4

 

II

33.2

30.0

3.3

0.7

 

III

11.4

10.4

2.8

0.8

 

IV

5.6

3.7

0.5

0.7

 

Unknown

17.8

26.1

69.5

90.4

Survival time (days)

Median

(1st and 3rd Quartile)

1279

(549; 2161)

1279

(580; 2130)

1552

(700; 2253)

1765

(975; 2557)

Censoring (in %)

Censored

84.6

88.5

88.1

90.5

Year of diagnosis

2000

10.2

9.7

10.8

15.1

 

2001

10.7

10.2

11.5

14.4

 

2002

11.1

10.6

10.0

10.9

 

2003

10.8

10.9

14.3

12.2

 

2004

10.7

10.7

12.8

14.6

 

2005

10.7

10.9

10.7

8.9

 

2006

11.5

11.6

10.0

10.8

 

2007

11.6

12.1

9.7

5.0

 

2008

12.7

13.4

10.3

8.1

Grading (in %)

1

10.6

10.6

3.4

5.7

 

2

54.2

53.7

0.3

0.2

 

3

30.0

30.1

0.2

0.2

 

4

0.2

0.1

< 0.1

0.1

 

Unknown

5.0

5.5

96.1

93.8

Radiotherapy (in %)

Yes

66.4

80.2

1.4

0.5

 

no

17.8

15.3

52.2

64.5

 

Unknown

15.8

4.5

46.4

35.0

Chemotherapy (in %)

Yes

46.1

47.9

1.8

1.4

 

No

37.4

36.7

51.8

63.9

 

Unknown

16.6

15.5

46.5

34.8

Hormone therapy (in %)

Yes

60.6

62.3

0.0

0.0

 

No

19.1

18.1

  
 

Unknown

20.3

19.6

  

Morphology (in %)

Infiltrating duct carcinoma

69.0

70.6

  
 

Lobular carcinoma

12.3

11.9

  
 

Infiltrating duct and lobular carcinoma

7.4

7.9

  
 

Nodular melanoma

  

12.4

13.6

 

Lentigo maligna melanoma

  

5.3

5.1

 

Superficial spreading melanoma

  

41.4

48.4

 

Others and NOS

10.5

9.6

41.0

32.8

Topography (in %)

Central portion of breast

5.3

5.1

  
 

Upper-inner quadrant of breast

9.3

9.6

  
 

Lower-inner quadrant of breast

4.6

4.7

  
 

Upper-outer quadrant of breast

35.7

36.3

  
 

Lower-outer quadrant of breast

6.3

6.3

  
 

Axillary tail of breast

0.2

0.1

  
 

Overlapping lesion of breast

8.9

8.2

  
 

Trunc

  

32.2

35.9

 

Extremity

  

46.7

50.1

 

Head/Neck

  

13.5

11.3

 

NOS

29.9

29.7

7.6

2.7

  1. * For T-, N-, M- and UICC-stage the mean frequencies of the five simulated data sets are provided. The other variables distributions are identical in all five data sets.