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Table 4 Simulation results for the current leukaemia-free survival estimator and the Markov model estimator of Klein et al.

From: Estimation of current cumulative incidence of leukaemia-free patients and current leukaemia-free survival in chronic myeloid leukaemia in the era of modern pharmacotherapy

 

Sample size 100

Sample size 1,000

 

CLFS estimator

Markov model estimator

CLFS estimator

Markov model estimator

Time

        
 

MAD* (%)

Coverage of the 95% CI** (%)

MAD* (%)

Coverage of the 95% CI** (%)

MAD* (%)

Coverage of the 95% CI** (%)

MAD* (%)

Coverage of the 95% CI** (%)

1 year

2.3

92.7

2.3

92.7

0.7

93.5

0.7

94.2

2 years

2.7

94.5

2.7

94.3

0.8

94.3

0.9

94.6

3 years

3.0

94.3

3.0

93.2

1.0

95.2

1.0

95.2

4 years

3.4

94.2

3.4

94.1

1.0

94.9

1.0

95.9

5 years

3.5

93.6

3.8

93.3

1.2

93.1

1.2

94.7

6 years

4.1

93.9

4.0

93.2

1.2

95.2

1.3

95.2

7 years

4.2

93.6

4.1

92.5

1.5

95.0

1.4

93.9

8 years

5.0

95.2

4.7

93.2

1.6

94.0

1.5

93.8

9 years

5.8

94.3

5.6

90.1

1.9

93.3

1.8

94.0

10 years

6.7

94.2

6.3

88.1

2.2

95.1

2.1

92.3

  1. * Median absolute deviation between the estimated and true curve.
  2. ** The proportion of 95% point-wise confidence intervals that contained the approximated true curve.