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Table 2 Summary of results reported in a systematic review of reviews2

From: Methodology in conducting a systematic review of systematic reviews of healthcare interventions

Review Tocolytic agent Birth >48 hrs (95% CI) Birth >7 days
(95% CI)
Birth >34 weeks
(95% CI)
Birth >37 weeks
(95% CI)
King 1988 Betamimetics compared with placebo or no treatment 12 trials
OR 0.59, (0.42-0.83)
Significant
- - 8 trials
OR 0.71
(0.53-0.96)
Significant
Coomarasamy et al 2002 Atosiban V placebo (2 trials)
Atosiban V beta-agonist (4 trials)
2 trials
RR 1.13,
(1.02-1.26)
Significant
4 trials
RR 1.07
(0.98-1.17)
Not significant
-
3 trials
RR 1.25
(1.09-1.44)
Significant
- -
Crowther et al 2002 Magnesium sulphate V placebo/no treatment or other tocolytic agent 11 trials
RR 0.85, (0.58-1.25)
Not significant
- No difference reported No difference reported
King et al 2003 Calcium channel blockers V any other tocolytic agent - RR 0.76, (0.60-0.97)
Significant
RR 0.83, (0.69-0.99)
Significant
RR 0.95, (0.83-1.09)
Not significant
Anotayanonth et al 2004 Betamimetics V Placebo 11 trials
RR 0.63, (0.53-0.75)
Significant
11 trials
RR 0.78, (0.68-0.90)
Significant
- 11 trials
RR 0.95, (0.88-1.03)
Not significant
King et al 2005 COX inhibitor V Placebo
COX inhibitor V any other tocolytic
2 trials
RR 0.20, CI 0.03-1.28
4 trials
RR 0.59, CI 0.34-1.02
2 trials
RR 0.41, CI 0.10-1.66
- 3 trials
RR 0.21, CI 0.07-0.62
3 trials
RR 0.53, CI 0.31-0.94
Whitworth & Quenby 2008 Oral betamimetic V placebo - - - RR 1.07,
(0.14-8.09)
Not significant
  1. 2 Reprinted from the European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 142, Smith V, Devane D, Begley CM, Clarke M, Higgins S. A systematic review and quality assessment of systematic reviews of randomised trials of interventions for preventing and treating preterm birth. 3-11, Copyright (2009), with permission from Elsevier.