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Table 1 Sensitivity and specificity (95% confidence intervals) for prototypes and scales at designated cut-offs

From: A population study comparing screening performance of prototypes for depression and anxiety with standard scales

Measure Criterion Sensitivity (95% CI) Specificity (95% CI) AUC (95%CI)
Depression     
   Full Scale (CES-D) ≥ 16 87.5% (71.0% - 96.5%) 72.4% (66.9% - 77.5%) 0.86 (0.81 - 0.92)
   Short form scale (CES-D SF) ≥ 8 84.4% (67.2% - 94.7%) 69.7% (64.0% - 74.9%) 0.84 (0.78 - 0.90)
   Depression prototype ≥ 2 81.3% (63.6% - 92.8%) 59.0% (53.1% - 64.7%) 0.73 (0.64 - 0.82)
   Depression short prototype ≥ 2 50.0% (31.9% - 68.1%) 75.5% (70.2% - 80.4%) 0.64 (0.54 - 0.73)
Generalised Anxiety Disorder     
   Full Scale (GAD-7) ≥ 10 60.6% (42.1% - 77.1%) 87.6% (83.3% - 91.1%) 0.83 (0.76 - 0.90)
   Short form scale (GAD-2) ≥ 3 57.6% (39.2% - 74.5%) 86.3% (81.8% - 90.0%) 0.81 (0.73 - 0.89)
   GAD prototype ≥ 3 90.9% (75.7% - 98.1%) 72.1% (66.5% - 77.2%) 0.87 (0.83 - 0.92)
   GAD short prototype ≥ 2 75.8% (57.7% - 88.9%) 66.0% (60.2% - 71.4%) 0.74 (0.65 - 0.83)
Social phobia     
   Full Scale (SPIN) ≥ 19 88.9% (51.8% - 99.7%) 81.3% (76.6% - 85.5%) 0.92 (0.83 - 1.00)
   Short form scale (Mini-SPIN) ≥ 6 66.7% (29.9% - 92.5%) 85.8% (81.4% - 89.4%) 0.90 (0.81 - 0.99)
   Social phobia prototype ≥ 3 66.7% (29.9% - 92.5%) 86.7% (82.4% - 90.2%) 0.81 (0.63 - 0.99)
   Social phobia short prototype ≥ 2 33.3% (7.5% - 70.1%) 84.8% (80.3% - 88.6%) 0.59 (0.43 - 0.76)
Panic disorder     
   Full Scale (PDSS-SR) ≥ 8 66.7% (22.3% - 95.7%) 95.6% (92.8% - 97.6%) 0.87 (0.69 - 1.00)
   Short form scale (PDSS-SR items 1 & 2) ≥ 4 66.7% (22.3% - 95.7%) 90.3% (86.5% - 93.3%) 0.88 (0.69 - 1.00)
   Panic disorder prototype ≥ 2 50.0% (11.8% - 88.2%) 81.3% (76.5% - 85.4%) 0.67 (0.44 - 0.91)
   Panic disorder short prototype ≥ 2 83.3% (35.9% - 99.6%) 51.9% (46.3% - 57.5%) 0.73 (0.51 - 0.95)
  1. Note: AUC: Area under the curve; CES-D: Center for Epidemiological Studies Depression scale; GAD: Generalised Anxiety Disorder; SPIN: Social Phobia Inventory; PDSS-SR: Panic Disorder Severity Scale - Self Report.