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Table 2 Formulae for the most commonly used simple indices of insulin resistance derived from fasting specimens and other specimens taken in the context of an oral glucose tolerance test (GTT).

From: Selection of the appropriate method for the assessment of insulin resistance

Index

Formula

Reference

GTT derived indices:

ISI-gly

2/[(INSp × GLYp)] + 1

[74]

ISI (composite)

1000/√{[fasting glucose (mg/dL) × fasting insulin (μU/mL)] × [mean glucose × mean insulin]}

[21]

Fasting sample indices:

HOMA-IR

Fasting glucose (mmol/L) ×fasting insulin (mU/L)/22.5

[36]

HOMA2-S

HOMA2 calculator version 2.2

[37]

FGIR

Fasting glucose (mg/dL)/Fasting insulin (mU/L)

[58]

Raynaud

40/Fasting insulin (mU/L)

[33]

Reciprocal insulin

1/fasting insulin (mU/L)

[34]

QUICKI

1/[log fasting insulin (mU/L) + log fasting glucose (mg/dL)]

[46]

FGIR

Fasting glucose (mg/dL)/Fasting insulin (mU/L)

[58]

  1. Key: GTT, oral glucose tolerance test; HOMA-IR, homeostasis model assessment insulin resistance; QUICKI, quantitative insulin sensitivity check index; FGIR, fasting glucose insulin ratio; ISI (composite), an index of whole-body insulin sensitivity; ISI-gly, insulin sensitivity glycemic index; INSp, insulinemic area; GLYp, glycemic area.