Response | Time to Progression | Stage 1 Drug Rejection | Stage 2 Drug Acceptance | Power | Alpha Error | ENnul /PESnul | ENalt /PESalt | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
r nul | r alt | ttp nul | ttp alt | r 1 | epd | r 1+r 2 | ttp | Â | Â | Â | Â |
0.05 | 0.2 | 3 | 6 | ≤ 0 | ≥ 5 | ≥ 5 | ≥ 5.25 | 0.815 | 0.035 | 26.8/0.21 | 29.7/0.02 |
0.05 | 0.2 | 3 | 7 | ≤ 0 | ≥ 5 | ≥ 5 | ≥ 6 | 0.828 | 0.02 | 26.8/0.22 | 29.8/0.01 |
0.05 | 0.2 | 4 | 7 | ≤ -1 | ≥ 16 | ≥ 5 | ≥ 6.25 | 0.821 | 0.074 | 30/0 | 30/0 |
0.05 | 0.2 | 4 | 8 | ≤ 0 | ≥ 4 | ≥ 5 | ≥ 7 | 0.812 | 0.035 | 26.8/0.21 | 29.6/0.02 |
0.05 | 0.2 | 5 | 8 | ≤ 0 | ≥ 9 | ≥ 5 | ≥ 7 | 0.825 | 0.15 | 29.99†/ 0.0002 | 29.99†/ 0.0005 |
0.05 | 0.2 | 6 | 9 | ≤ 0 | ≥ 10 | ≥ 5 | ≥ 8 | 0.816 | 0.2 | 29.99/ 0.00001 | 29.99/ 0.0001 |
0.1 | 0.3 | 3 | 7 | ≤ 2 | ≥ 5 | ≥ 7 | ≥ 6 | 0.854 | 0.03 | 24.4/0.37 | 29.5/0.03 |
0.1 | 0.3 | 4 | 7 | ≤ 2 | ≥ 4 | ≥ 7 | ≥ 6 | 0.829 | 0.09 | 28.9/0.38 | 24.4/0.07 |
0.1 | 0.3 | 4 | 8 | ≤ 1 | ≥ 4 | ≥ 7 | ≥ 6.75 | 0.86 | 0.055 | 26.2/0.25 | 29.6/0.03 |
0.2 | 0.4 | 5 | 8 | ≤ 1 | ≥ 7 | ≥ 10 | ≥ 6.75 | 0.867 | 0.23 | 29.97/ 0.002 | 29.99/ 0.0004 |
0.2 | 0.4 | 5 | 9 | ≤ 3 | ≥ 3 | ≥ 10 | ≥ 7.5 | 0.813 | 0.13 | 24.6/0.36 | 28.6/0.09 |
0.3 | 0.5 | 5 | 8 | ≤ 4 | ≥ 3 | ≥ 12 | ≥ 6.75 | 0.828 | 0.29 | 25.7/0.28 | 28.4/0.1 |
0.3 | 0.5 | 6 | 9 | ≤ 4 | ≥ 3 | ≥ 12 | ≥ 7.5 | 0.843 | 0.35 | 26.7/0.22 | 28.7/0.09 |