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Table 3 Mean average DDD use 1 of all broad-spectrum antibiotics and corresponding limits of agreement 2 (DDD use range) for different registration intervals (all wards combined).

From: Pharmacy sales data versus ward stock accounting for the surveillance of broad-spectrum antibiotic use in hospitals

Interval

Defined daily doses (DDDs)

Antibiotics

Mean use

Use range (- %; + %)

Mean difference

1 week

   

   All

152.8

144.1 - 167.5 (9.6; 9.6)

0.007

   Parenteral

92.8

85.0 - 100.6 (8.4; 8.4)

-0.003

   Oral

60.0

23.9 - 96.2 (60.2; 60.4)

0.079

2 weeks

   

   All

305.6

287.1 - 324.1 (6.1; 6.1)

0.014

   Parenteral

185.6

175.5 - 195.7 (5.5; 5.4)

-0.006

   Oral

120.0

74.9 - 165.4 (37.6; 37.8)

0.158

3 weeks 3

   

   All

466.0

442.8 - 489.2 (5.0; 5.0)

0.031

   Parenteral

288.7

274.5 - 294.9 (3.5; 3.6)

0.050

   Oral

181.3

120.7 - 241.7 (33.4; 33.3)

-0.102

4 weeks 3

   

   All

621.3

600.6 - 642.1 (3.3; 3.3)

0.042

   Parenteral

379.6

367.6 - 391.8 (3.2; 3.2)

0.067

   Oral

241.7

191.6 - 291.5 (20.7; 20.6)

-0.136

  1. 1 Sum of averages of paired results (pharmacy sales DDDs and ward stock DDDs)
  2. 2 Limits of agreement according to Bland-Altman statistics are expressed as the range of DDDs and percent DDD deviation below and over the mean average use
  3. 3 Weeks 12 and 26 were discarded (see Methods)