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Table 1 Calculation of effect sizes (Cohen's d) for early and late treatment as assessed with scale F A and F B .

From: Additive scales in degenerative disease - calculation of effect sizes and clinical judgment

 

Scale F A

Scale F B

Treatment 1 early

0.4796

0.5693

Treatment 1 late

0.5736

0.6039

Treatment 2 early

0.5579

0.4624

Treatment 2 late

0,6005

0.5681

  1. In scale F A : F A (t; a i , b i , c i , i = 1, 2) = 3/8 f 1(t; a 1, b 1, c 1) + 5/8 f 2 (t; a 2, b 2, c 2). In scale F B : F B (t; a i , b i , c i , i = 1, 2) = 2/3 f 1(t; a 1, b 1, c 1) + 1/3 f 2 (t; a 2, b 2, c 2). A treatment effect of 30% is assumed for f 1 (Treatment 1) or f 2 (Treatment 2).