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Table 1 Catalogue of simulation designs

From: Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: A simulation study

Design

Scenario

Number of centres

Centre size

ICC

Balance

1

45

4

 
 

2

18

10

 
 

3

6

30

 

Chance imbalance

4

45

4

 
 

5

18

10

0 - 0.75

 

6

6

30

 

Blocking

(size = 2)

7

17

1, 1, 4, 5, 5, 5, 8, 8, 10, 10, 10

 

Blocking

(size = 4)

8

17

10, 15, 15, 20, 25, 28

 

Blocking

(size = 6)

9

46

Same as Table 2

0.125

  1. ICC: Intraclass (intracentre) correlation