Table 1 Catalogue of simulation designs
| Design | Scenario | Number of centres | Centre size | ICC |
|---|---|---|---|---|
| Balance | 1 | 45 | 4 | |
| 2 | 18 | 10 | ||
| 3 | 6 | 30 | ||
| Chance imbalance | 4 | 45 | 4 | |
| 5 | 18 | 10 | 0 - 0.75 | |
| 6 | 6 | 30 | ||
|
Blocking (size = 2) | 7 | 17 | 1, 1, 4, 5, 5, 5, 8, 8, 10, 10, 10 | |
|
Blocking (size = 4) | 8 | 17 | 10, 15, 15, 20, 25, 28 | |
|
Blocking (size = 6) | 9 | 46 | Same as Table 2 | 0.125 |