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Table 2 Estimates of treatment effects for MS clinical trials in Japan

From: Alternative statistical methods for estimating efficacy of interferon beta-1b for multiple sclerosis clinical trials

Models Parameter Estimates Standard Error Hazard Ratio [95%CI] P value
1: Time-to-first-event Cox regression -0.263 0.194 0.769 [0.526, 1.123] 0.174
2: AG model -0.377 0.170 0.686 [0.492, 0.957] 0.027
3-1: PWP-T model -0.268 0.132 0.765 [0.591, 0.989] 0.041
3-2: PWP-G model -0.306 0.135 0.736 [0.565, 0.960] 0.024
4: WLW model -0.489 0.231 0.613 [0.390, 0.965] 0.035
5: LWA model -0.427 0.195 0.653 [0.445, 0.957] 0.029
6: Poisson regression model -0.371 0.171 0.690 [0.493, 0.965] 0.030
7: GEE-Poisson model -0.352 0.169 0.703 [0.505, 0.980] 0.037