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Table 3 Parameter estimates from flexible parametric survival models

From: Estimating and modelling cure in population-based cancer studies within the framework of flexible parametric survival models

Parameter Standard FPM
splines calculated backwards
Restricted FPM
incorporating a cure proportion
Restricted FPM
including time-dependent effects
Intercept 0.385 (0.032) 0.350 (0.031) 0.279 (0.033)
Age group    
<50 - - -
50-59 0.089 (0.034) 0.089 (0.034) 0.085 (0.035)
60-69 0.214 (0.030) 0.212 (0.031) 0.184 (0.031)
70-79 0.385 (0.030) 0.382 (0.030) 0.284 (0.031)
80+ 0.788 (0.032) 0.785 (0.032) 0.532 (0.035)
LRT p <0.0001 p <0.0001 p <0.0001
Calendar period   
1953-1964 - - -
1965-1974 -0.339 (0.029) -0.340 (0.029) -0.264 (0.032)
1975-1984 -0.741 (0.028) -0.743 (0.028) -0.585 (0.030)
1985-1994 -0.922 (0.027) -0.924 (0.027) -0.769 (0.029)
1995-2003 -1.190 (0.027) -1.194 (0.027) -1.025 (0.030)
LRT p <0.0001 p <0.0001 p <0.0001
LRT comparing to the previous model p <0.0001 p <0.0001
AIC 92285.22 92323.95 91590.12
BIC 92398.63 92429.26 91825.04
  1. Parameter estimates (standard errors) from flexible parametric survival models
  2. FPM, flexible parametric survival model; LRT, likelihood ratio test; AIC, Akaike's information criterion; BIC, Bayesian information criterion.