From: Designing cost-efficient randomized trials by using flexible recruitment strategies

Calculated costs | Simulated costs | Simulated actual power | Simulated actual type I error |
Marginal treatment effects (λ_{1})
| |||||||
---|---|---|---|---|---|---|---|---|---|---|---|

$\frac{\mathit{C}\mathit{\text{pre}}}{\mathit{C}\mathit{\text{pre}}+\mathit{C}\mathit{\text{scr}}}$† |
ρ ‡
| Single stage | Two stage | Single stage | Two stage | Single stage | Two stage | Single stage | Two stage | Single stage | Two stage |

0.10 | 0.70 | $117.5 K | $90.8 K | $118.3 K | $92.0 K | 0.91 | 0.91 | 0.05 | 0.05 | 0.27 | 0.33 |

0.20 | 0.70 | $117.5 K | $99.9 K | $118.4 K | $101.5 K | 0.90 | 0.90 | 0.06 | 0.05 | 0.27 | 0.31 |

0.30 | 0.70 | $117.5 K | $105.6 K | $118.3 K | $108.3 K | 0.89 | 0.91 | 0.05 | 0.05 | 0.27 | 0.30 |

0.40 | 0.70 | $117.5 K | $109.5 K | $118.3 K | $112.0 K | 0.89 | 0.91 | 0.06 | 0.06 | 0.27 | 0.30 |

0.50 | 0.70 | $117.5 K | $112.4 K | $118.4 K | $113.4 K | 0.90 | 0.91 | 0.04 | 0.05 | 0.27 | 0.29 |

0.33 | 0.30 | $117.5 K | $116.8 K | $118.5 K | $118.9 K | 0.90 | 0.91 | 0.05 | 0.05 | 0.27 | 0.28 |

0.33 | 0.45 | $117.5 K | $114.5 K | $118.5 K | $115.8 K | 0.89 | 0.90 | 0.04 | 0.05 | 0.27 | 0.28 |

0.33 | 0.60 | $117.5 K | $110.5 K | $118.5 K | $113.3 K | 0.89 | 0.91 | 0.05 | 0.05 | 0.27 | 0.30 |

0.33 | 0.75 | $117.5 K | $105.2 K | $118.3 K | $107.6 K | 0.90 | 0.91 | 0.05 | 0.06 | 0.27 | 0.30 |

0.33 | 0.90 | $117.5 K | $98.0 K | $118.5 K | $99.8 K | 0.90 | 0.91 | 0.06 | 0.04 | 0.27 | 0.31 |