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Table 4 Power calculations for different prevalences of a single risk factor for trial discontinuation; RCT, randomized controlled trial; OR, odds ratio

From: Learning from failure - rationale and design for a study about discontinuation of randomized trials (DISCO study)

Prevalence (%) of risk factor
Completed RCTs RCTs discontinued due to slow accrual Study power (%) to detect OR = 2.0
10 18 65
20 33 88
30 46 95
40 57 96