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Table 1 Simulation input parameters

From: Simulation evaluation of statistical properties of methods for indirect and mixed treatment comparisons

Parameters

Values

Number of studies

3×40; 3×20; 3×10; 3×5; 3×1; 5/1/5

Number of patients per study

2×100

Between trial heterogeneity: Ï„2

0.00; 0.05; 0.10; 0.15

Treatment effect: log OR, θ12

log(0.8)

Treatment effect: log OR, θ13

log(0.8); log(0.6)

Bias: ROR12

0.00; 0.80

Bias: ROR13

0.00; 0.80

Bias: ROR23

0.00; 0.80

Baseline risk: P1

10%; 20%

  1. (Note: these input values could be combined differently for a large number of possible simulation scenarios).