Table 5 Reasons for Antipsychotic Discontinuation/Continuation questionnaire assessing the clinician’s perspective (RAD-Q)
Item | Scoring | Item | Scoring |
|---|---|---|---|
RAD-Q Discontinuation | RAD-Q Continuation | ||
1. This medication did not sufficiently improve positive symptoms (e.g., hallucinations, delusions). | A | 30. The medication has no serious safety issues that are dangerous and potentially life-threatening for this patient (e.g., seizures, heart arrhythmia, agranulocytosis). | A |
2. This medication made positive symptoms worse. | A | 31. Benefits for positive symptoms (e.g., hallucinations, delusions). | A |
3. This medication did not sufficiently improve negative symptoms (e.g., flat affect, lack of motivation). | A | 32. Benefits for negative symptoms (e.g., flat affect, lack of motivation). | A |
4. This medication made negative symptoms worse. | A | 33. Benefits for the patient’s mood (e.g., depression). | A |
5. This medication did not sufficiently improve the patient’s mood (e.g., depression). | A | 34. Benefits for cognition (e.g., planning, attention, memory). | A |
6. The medication made the patient’s mood worse. | A | 35. Benefits for functional status (e.g., self-care activities of daily living, or work). | A |
7. This medication did not sufficiently improve cognition (e.g., planning, attention, memory). | A | 36. Financial cost of medication. | A |
8. This medication made cognition worse. | A | 37. The patient’s insurance adequately covers this medication. | A |
9. This medication did not sufficiently improve functional status (e.g., the patient’s ability to work or live independently). | A | 38. The patient is willing/able to negotiate the health-care system to obtain this drug (e.g., getting prescriptions filled, scheduling/attending appointments). | A |
10. This medication made functional status worse. | A | 39. There are no problems with transportation (e.g., getting to the pharmacy to refill medication). | A |
11. A medication-related serious safety issue that was dangerous and potentially life-threatening (e.g., seizures, heart arrhythmia, agranulocytosis). | A | 40. Social support (e.g., friends or family support the patient in taking this medication). | A |
12-16. Please list up to 5 non-life threatening side effects experienced by the patient that were reasons for discontinuing this medication. | A | 41. Patient perceptions of improvement (e.g., the patient believed he/she was now “better” and wants to continue taking the medication). | A |
17. Financial cost of the medication. | A | 42. The patient has formed a therapeutic alliance or connection with members of the treatment team. | A |
18. The patient’s insurance did not adequately cover this medication. | A | 43. Another person told this patient to continue taking the medication (if so, what is the relationship of this person to the patient?). | A |
19. Difficulty negotiating the health-care system (e.g., getting prescriptions filled, scheduling/attending appointments). | A | 44. The patient has already tried other antipsychotics that have not been as effective and/or tolerable. | A |
20. Problems with transportation (e.g., getting to the pharmacy to refill medication). | A | 45-46. Other: Specify. | |
21. Social support (e.g., friends or family did not support patient in taking this medication). | A | 47-51. Please list up to 5 side effects the patient experiences from this antipsychotic. | A |
22. Patient believes he/she no longer needed the medication because he/she was now “better.” | A | Of all the reasons listed in items 30–51, is there one that you consider to be the most important reason for continuing this medication? | B |
23. The patient believed the medication was causing symptoms to become worse. | A | ||
24. The patient was unable to connect with members of the treatment team. | A | ||
25. Another person told this patient to stop the medication (if so, what is the relationship of the person to the patient?). | A | ||
26. The patient wished to try an antipsychotic new to the market. | A | ||
27. Potential interactions with another drug prescribed for this patient? | A | ||
28. The patient was not adhering to the medication regimen. | A | ||
29. The patient developed a new medical condition and this antipsychotic may have exacerbated the condition. | A | ||
Of all the reasons listed in items 1–29, is there one that you consider to be the most important reason for discontinuing this medication? | B | ||