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Table 1 Comparison of network meta-analysis (NMA)-based estimates between the 2 adjustment models applied to published data and the standard NMA model applied to US Food and Drug Administration (FDA) data and to published data

From: Adjustment for reporting bias in network meta-analysis of antidepressant trials

 

FDA data

Published data

 

Standard NMA model

Regression model

Selection model

Standard NMA model

 

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Θ BUP

0.176 (0.081)

0.043 (0.256)

0.229 (0.121)

0.271 (0.139)

Θ CIT

0.240 (0.074)

0.081 (0.171)

0.254 (0.073)

0.306 (0.076)

Θ DUL

0.300 (0.054)

0.166 (0.190)

0.340 (0.066)

0.402 (0.058)

Θ ESC

0.310 (0.067)

0.165 (0.193)

0.311 (0.070)

0.357 (0.068)

Θ FLU

0.256 (0.081)

0.004 (0.160)

0.215 (0.068)

0.271 (0.074)

Θ MIR

0.351 (0.070)

0.206 (0.331)

0.424 (0.110)

0.567 (0.092)

Θ NEF

0.256 (0.076)

0.112 (0.260)

0.348 (0.094)

0.437 (0.094)

Θ PAR

0.426 (0.063)

0.267 (0.346)

0.438 (0.105)

0.593 (0.078)

Θ PAR CR

0.323 (0.101)

0.174 (0.187)

0.309 (0.083)

0.354 (0.085)

Θ SER

0.252 (0.077)

0.210 (0.231)

0.359 (0.094)

0.419 (0.094)

Θ VEN

0.395 (0.071)

0.199 (0.224)

0.403 (0.092)

0.504 (0.075)

Θ VEN XR

0.398 (0.094)

0.261 (0.273)

0.423 (0.110)

0.506 (0.107)

Ï„

0.060 (0.037)

0.031 (0.024)

0.024 (0.019)

0.032 (0.025)

  1. Data are posterior means and standard deviations of the basic parameters (Θ), the between-trial heterogeneity (τ).