Table 1 Health equity plausibility algorithm questions

Question 1:

Are there differences in patient/community/ population characteristics (e.g. underlying pathophysiology, comorbidities, patient attitudes, etc.) that are likely to create important differences in the magnitude of relative effect of the intervention versus the control for the outcome of interest?

Question 2:

Are there differences in the way that the intervention is delivered (e.g. provider compliance, provider skill, technical resources, availability of drugs/treatments) that are likely to create important differences in the magnitude of the relative effect of the intervention versus the control for the outcome of interest?

Question 3:

Are there differences in the comparator across patient, community or population that are likely to create important differences in magnitude of relative effects?