Is it possible to estimate the minimal clinically important treatment effect needed to change practice in preterm birth prevention? Results of an obstetrician survey used to support the design of a trial

Table 5 Feasibility of trials

What would be the best outcome measure for a trial? (n = 544)
	Outcome	Response
	prolongation of gestation		95 (18.1%)
	decreased fetal morbidity		379 (72.2%)
	decreased fetal mortality		50 (9.5%)
	decreased maternal morbidity		1 (0.2%)
	missing		19
Would you take part in a trial?
	Vaginal Progesterone in multiple pregnancies (n = 544)	Progesterone IM in singleton pregnancies (n = 544)	Cerclage (n = 544)
yes	450 (84.1%)	410 (77.5%)	239 (45.5%)
no	85 (15.9%)	119 (22.5%)	288 (54.6%)
missing	9	15	17

ISSN: 1471-2288