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Table 3 Comparisons of publishe d and locally-estimated multivariate predictive functions after inclusion of 942 subjects with incomplete baseline and follow-up measurements using multiple imputations

From: The ARIC predictive model reliably predicted risk of type II diabetes in Asian populations

 

SAHS

ARIC

Framingham*

Risk factor at baseline

Locally-estimated

(95% CI)

Published

Locally-estimated

(95% CI)

Published

Locally-estimated

(95% CI)

Published

Age (years)

-0.002 (-0.018; 0.014)

0.028

-0.014 (-0.031; 0.003)

0.0173

NA

NA

Gender

0.182 (-0.207; 0.570)

0.661

NA

NA

NA

NA

Ethnicity

0.371 (0.024; 0.719)

0.412

0.412 (0.064; 0.759)

0.4433

NA

NA

FPG (mg/dl)

0.094 (0.055; 0.134)

0.079

0.080 (0.056; 0.104)

0.0880

NA

NA

IFG

NA

NA

NA

NA

1.693 (1.276; 2.110)

1.98

SBP (mm Hg)

0.012 (0.001; 0.023)

0.018

0.011 (0.000; 0.022)

0.0111

0.584 (0.215; 0.953)

0.50

Triglyceride(mg/dl)

NA

NA

0.000 (-0.001;0.001)

0.0027

0.577 (0.179; 0.976)

0.58

HDL (mg/dl)

-0.021 (-0.039;-0.004)

-0.039

-0.012 (-0.029; 0.005)

-0.0122

0.303 (-0.051; 0.656)

0.94

BMI (kg/m2)

0.080 (0.057; 0.104)

0.070

NA

NA

NA

NA

BMI (overweight)

NA

NA

NA

NA

0.755 (0.389;1.12)

0.30

BMI (obese)

NA

NA

NA

NA

1.209 (0.689;1.729)

0.92

Waist (cm)

NA

NA

0.045 (0.026; 0.063)

0.0273

NA

NA

Height (cm)

NA

NA

-0.030 (-0.050;-0.011)

-0.0326

NA

NA

Family history of T2DM

0.513 (0.190; 0.837)

0.481

0.541 (0.215; 0.866)

0.4981

0.625 (0.300; 0.949)

0.57

  1. Bold and italicized fonts: Estimates from local models whose 95% confidence intervals do not overlap with the published estimates, i.e., we assumed that the published estimates were the true values in the hypothesis testing)
  2. *Categorical variables are used for the Framingham model with the following rule: fasting glucose level: (1 = 100 - 125 mg/dL, 0 ≤ 100 mg/dL), overweight (1 = BMI ≥ 25 & BMI < 30, 0 = otherwise), obese (1 = BMI ≥ 30, 0 = otherwise), low high density lipoprotein (HDL) (1 = HDL < 40 mg/dL in men or < 50 mg/dL in women, 0 = otherwise), high triglyceride level (1 ≥ 150 mg/dL, 0 = otherwise), elevated blood pressure (systolic blood pressure ≥ 130 or diastolic blood pressure ≥ 85 mm Hg, 0 = otherwise)