FTR strata | STR strata | |||||
---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | |
Variables entering in z e only | ||||||
Causal nephropathy (recurrent / non recurrent) | 1.12 | 0.90-1.39 | 0.3031 | - | - | - |
History of diabetes (positive / negative) | 1.28 | 0.95-1.72 | 0.1001 | - | - | - |
History of hypertension (positive / negative) | 0.88 | 0.68-1.14 | 0.3270 | - | - | - |
History of cardiac disease (positive / negative) | 1.35 | 1.10-1.66 | 0.0042 | - | - | - |
History of vascular disease (positive / negative) | 1.11 | 0.85-1.47 | 0.4433 | - | - | - |
History of dyslipemia (positive / negative) | 1.19 | 0.95-1.49 | 0.1263 | - | - | - |
History of hepatitis B/C (positive / negative) | 0.97 | 0.65-1.46 | 0.9091 | - | - | - |
History of malignancy (positive / negative) | 1.21 | 0.87-1.67 | 0.2646 | - | - | - |
Body mass index (≥ 30 kg.m-2 / < 30 kg.m-2) | 1.54 | 1.13-2.08 | 0.0057 | - | - | - |
Anti-class I PRA (positive / negative) | 1.39 | 1.07-1.82 | 0.0153 | - | - | - |
Anti-class II PRA (positive / negative) | 0.98 | 0.73-1.31 | 0.8857 | - | - | - |
Donor status (deceased/living) | 2.06 | 1.27-3.36 | 0.0036 | - | - | - |
Donor EBV serology (positive / negative) | 1.65 | 1.07-2.54 | 0.0235 | - | - | - |
Number of HLA-A-B-DR mismatches (> 4 / ≤ 4) | 1.33 | 1.01-1.75 | 0.0397 | - | - | - |
Induction therapy (depleting / non depleting) | 0.88 | 0.70-1.11 | 0.2742 | - | - | - |
Cold ischemia time (≥ 24 h / < 24 h) | 1.20 | 0.97-1.49 | 0.0894 | - | - | - |
Variables entering in z c and z s | ||||||
Transplantation period (< 2005 / ≥ 2005) | 1.42 | 1.09-1.86 | 0.0099 | 0.94 | 0.54-1.64 | 0.8295 |
Recipient gender (male / female) | 1.17 | 0.91-1.50 | 0.2200 | 0.63 | 0.40-1.02 | 0.0581 |
Recipient age (≥ 55 years / < 55 years) | 1.36 | 1.03-1.78 | 0.0274 | 1.60 | 0.95-2.72 | 0.0785 |
Donor age (≥55 years / <55 years) | 1.36 | 1.04-1.77 | 0.0238 | 0.60 | 0.35-1.05 | 0.0725 |
Variables entering in z r only | ||||||
Donor gender (male / female) | - | - | - | 1.51 | 0.97-2.36 | 0.0674 |
Waiting time before regraft ≥ 3 years | - | - | - | 1.99 | 1.29-3.07 | 0.0019 |