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Table 3 Results of the stratified Cox model based on 2746 patients with 2206 FTR and 540 STR (26 STR presenting missing data for the waiting time before re-transplantation were excluded)

From: Comparison of the risk factors effects between two populations: two alternative approaches illustrated by the analysis of first and second kidney transplant recipients

 

FTR strata

STR strata

 

HR

95% CI

p-value

HR

95% CI

p-value

Variables entering in z e only

      

Causal nephropathy (recurrent / non recurrent)

1.12

0.90-1.39

0.3031

-

-

-

History of diabetes (positive / negative)

1.28

0.95-1.72

0.1001

-

-

-

History of hypertension (positive / negative)

0.88

0.68-1.14

0.3270

-

-

-

History of cardiac disease (positive / negative)

1.35

1.10-1.66

0.0042

-

-

-

History of vascular disease (positive / negative)

1.11

0.85-1.47

0.4433

-

-

-

History of dyslipemia (positive / negative)

1.19

0.95-1.49

0.1263

-

-

-

History of hepatitis B/C (positive / negative)

0.97

0.65-1.46

0.9091

-

-

-

History of malignancy (positive / negative)

1.21

0.87-1.67

0.2646

-

-

-

Body mass index (≥ 30 kg.m-2 / < 30 kg.m-2)

1.54

1.13-2.08

0.0057

-

-

-

Anti-class I PRA (positive / negative)

1.39

1.07-1.82

0.0153

-

-

-

Anti-class II PRA (positive / negative)

0.98

0.73-1.31

0.8857

-

-

-

Donor status (deceased/living)

2.06

1.27-3.36

0.0036

-

-

-

Donor EBV serology (positive / negative)

1.65

1.07-2.54

0.0235

-

-

-

Number of HLA-A-B-DR mismatches (> 4 / ≤ 4)

1.33

1.01-1.75

0.0397

-

-

-

Induction therapy (depleting / non depleting)

0.88

0.70-1.11

0.2742

-

-

-

Cold ischemia time (≥ 24 h / < 24 h)

1.20

0.97-1.49

0.0894

-

-

-

Variables entering in z c and z s

      

Transplantation period (< 2005 / ≥ 2005)

1.42

1.09-1.86

0.0099

0.94

0.54-1.64

0.8295

Recipient gender (male / female)

1.17

0.91-1.50

0.2200

0.63

0.40-1.02

0.0581

Recipient age (≥ 55 years / < 55 years)

1.36

1.03-1.78

0.0274

1.60

0.95-2.72

0.0785

Donor age (≥55 years / <55 years)

1.36

1.04-1.77

0.0238

0.60

0.35-1.05

0.0725

Variables entering in z r only

      

Donor gender (male / female)

-

-

-

1.51

0.97-2.36

0.0674

Waiting time before regraft ≥ 3 years

-

-

-

1.99

1.29-3.07

0.0019

  1. PRA, panel reactive antibody; EBV, Epstein-Barr virus; HLA, human leukocyte antigen.