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Table 3 Design parameters for the SORCE trial

From: Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome

Year Trial plan Hypothetical
  DFS prob. HR (PH) HR (non-PH)
1 0.779 0.75 0.65
3 0.635 0.75 0.75
5 0.576 0.75 0.85
7 0.532 0.75 0.9
10 0.488 0.75 1.0
13 0.454 0.75 1.0
  1. “DFS prob.” denotes survival probabilities for the disease-free survival outcome. PH and non-PH refer respectively to designs with (as per protocol) and without (hypothetical) proportional hazards of the treatment effect.