From: On the proportional hazards model for occupational and environmental case-control analyses
Population size | Case: control ratio | Intensity patterns (a) | Exposure variables | β | Method (b) | Relative bias (%) (c) | Relative bias / Cox pop (%) (c) | Relative efficiency (d) | RMSE × 10-3 (e) | ASE/SDE (e) | Cov. rate (e) |
---|---|---|---|---|---|---|---|---|---|---|---|
1 000 | 1:1 | A | Intensity | 1.39 | WC1 | 2.9 | 2.4 | 0.61 | 158 | 0.87 | 89.1 |
WC2 | - | - | - | - | 1.17 | 97.5 | |||||
CLR | 5.9 | 5.5 | 0.14 | 327 | 0.95 | 96.5 | |||||
ULR | −2.6 | −3.0 | 0.31 | 218 | 0.97 | 93.1 | |||||
Duration | 0.05 | WC1 | 3.3 | 2.0 | 0.41 | 14 | 0.82 | 88.3 | |||
WC2 | - | - | - | - | 1.08 | 97.1 | |||||
CLR | 6.2 | 4.6 | 0.19 | 20 | 0.96 | 95.7 | |||||
ULR | −5.3 | −6.6 | 0.35 | 15 | 1.03 | 95.1 | |||||
1:1 | B | Intensity | 1.39 | WC1 | 2.6 | 2.7 | 0.59 | 158 | 0.88 | 89.9 | |
WC2 | - | - | - | - | 1.18 | 98.7 | |||||
CLR | 3.4 | 3.4 | 0.14 | 315 | 0.94 | 94.9 | |||||
ULR | −3.8 | −3.7 | 0.31 | 219 | 0.98 | 92.0 | |||||
Duration | 0.05 | WC1 | 2.0 | 2.4 | 0.45 | 14 | 0.79 | 88.3 | |||
WC2 | - | - | - | - | 1.04 | 96.1 | |||||
CLR | 1.9 | 2.2 | 0.21 | 21 | 0.94 | 94.2 | |||||
ULR | −8.6 | −8.3 | 0.39 | 16 | 0.99 | 93.4 | |||||
5 000 | 1:1 | B | Intensity | 1.39 | WC1 | 7.3 | 9.3 | 0.20 | 254 | 0.72 | 76.1 |
WC2 | - | - | - | - | 0.85 | 85.6 | |||||
CLR | −0.9 | 0.7 | 0.10 | 325 | 0.87 | 89.8 | |||||
ULR | −3.3 | −1.7 | 0.23 | 219 | 0.92 | 91.8 | |||||
Duration | 0.05 | WC1 | 1.6 | 7.0 | 0.17 | 28 | 0.79 | 89.0 | |||
WC2 | - | - | - | - | 0.90 | 93.0 | |||||
CLR | −15.7 | −12.5 | 0.19 | 27 | 0.92 | 90.8 | |||||
ULR | −15.4 | −11.9 | 0.32 | 22 | 0.94 | 90.4 | |||||
1:2 | B | Intensity | 1.39 | WC1 | −0.3 | 1.6 | 0.25 | 203 | 0.78 | 86.7 | |
WC2 | - | - | - | - | 0.93 | 92.8 | |||||
CLR | −3.0 | −1.2 | 0.22 | 218 | 0.98 | 93.1 | |||||
ULR | −3.5 | −1.7 | 0.34 | 181 | 0.96 | 91.8 | |||||
Duration | 0.05 | WC1 | −3.4 | 1.3 | 0.27 | 22 | 0.85 | 89.2 | |||
WC2 | - | - | - | - | 1.00 | 94.5 | |||||
CLR | −10.0 | −6.5 | 0.33 | 21 | 0.95 | 92.3 | |||||
ULR | −10.2 | −6.5 | 0.45 | 18 | 0.96 | 93.3 | |||||
1:4 | B | Intensity | 1.39 | WC1 | −5.3 | −3.6 | 0.37 | 191 | 0.80 | 85.0 | |
WC2 | - | - | - | - | 0.99 | 91.5 | |||||
CLR | −3.9 | −2.2 | 0.36 | 187 | 0.93 | 89.8 | |||||
ULR | −3.6 | −1.8 | 0.47 | 164 | 0.93 | 91.0 | |||||
Duration | 0.05 | WC1 | −10.6 | −6.5 | 0.39 | 19 | 0.86 | 88.9 | |||
WC2 | - | - | - | - | 1.06 | 94.6 | |||||
CLR | −11.1 | −7.3 | 0.49 | 17 | 0.95 | 91.7 | |||||
ULR | −10.9 | −6.9 | 0.58 | 16 | 0.95 | 92.6 |