From: On the proportional hazards model for occupational and environmental case-control analyses
Model | Intensity patterns (a) | Exposure variables | β | Method (b) | Relative bias (%) (c) | Relative bias / Cox pop (%) (c) | Relative efficiency (d) | RMSE × 10-3 (e) | ASE/SDE (e) | Cov. rate (e) |
---|---|---|---|---|---|---|---|---|---|---|
2 | A | Intensity | 1.39 | WC1 | 3.7 | 2.7 | 0.60 | 164 | 0.86 | 91.1 |
WC2 | - | - | - | - | 1.18 | 98.3 | ||||
CLR | 9.5 | 8.3 | 0.09 | 435 | 0.82 | 96.3 | ||||
ULR | −2.9 | −3.9 | 0.28 | 230 | 0.97 | 94.1 | ||||
Duration | 0.05 | WC1 | 1.5 | 1.9 | 0.44 | 16 | 0.80 | 88.5 | ||
WC2 | - | - | - | - | 1.05 | 95.7 | ||||
CLR | 4.9 | 4.7 | 0.13 | 29 | 0.84 | 95.5 | ||||
ULR | −11.9 | −11.8 | 0.36 | 19 | 1.01 | 93.6 | ||||
Age at first exposure | −0.11 | WC1 | 4.7 | 3.1 | 0.44 | 32 | 0.79 | 86.3 | ||
WC2 | - | - | - | - | 1.04 | 95.3 | ||||
CLR | 9.9 | 7.7 | 0.18 | 50 | 0.92 | 95.1 | ||||
ULR | 0.4 | −1.2 | 0.39 | 33 | 1.00 | 95.1 | ||||
B | Intensity | 1.39 | WC1 | 3.1 | 2.8 | 0.64 | 161 | 0.88 | 90.1 | |
WC2 | - | - | - | - | 1.19 | 98.4 | ||||
CLR | 6.9 | 6.5 | 0.10 | 405 | 0.84 | 94.1 | ||||
ULR | −4.4 | −4.7 | 0.32 | 229 | 0.98 | 93.3 | ||||
Duration | 0.05 | WC1 | 1.3 | 1.3 | 0.49 | 16 | 0.82 | 90.4 | ||
WC2 | - | - | - | - | 1.09 | 96.5 | ||||
CLR | 5.6 | 5.0 | 0.17 | 27 | 0.91 | 95.0 | ||||
ULR | −12.7 | −12.8 | 0.37 | 19 | 1.00 | 92.9 | ||||
Age at first exposure | −0.11 | WC1 | 3.6 | 2.8 | 0.51 | 30 | 0.83 | 89.8 | ||
WC2 | - | - | - | - | 1.09 | 96.5 | ||||
CLR | 7.7 | 6.1 | 0.17 | 53 | 0.87 | 94.7 | ||||
ULR | −1.7 | −2.6 | 0.40 | 34 | 0.99 | 95.5 | ||||
3 | A | Intensity | 1.39 | WC1 | 3.4 | 3.0 | 0.58 | 165 | 0.84 | 90.3 |
WC2 | - | - | - | - | 1.13 | 97.0 | ||||
CLR | 6.0 | 5.5 | 0.14 | 333 | 0.92 | 95.9 | ||||
ULR | −1.5 | −1.9 | 0.33 | 213 | 0.99 | 94.2 | ||||
Duration | 0.05 | WC1 | 0.3 | 0.0 | 0.47 | 23 | 0.80 | 88.7 | ||
WC2 | - | - | - | - | 1.05 | 96.1 | ||||
CLR | 5.2 | 5.3 | 0.24 | 32 | 0.93 | 95.1 | ||||
ULR | −2.7 | −2.7 | 0.40 | 24 | 0.98 | 95.1 | ||||
Time since cessation | 0.04 | WC1 | 0.8 | 2.3 | 0.43 | 27 | 0.78 | 87.3 | ||
WC2 | - | - | - | - | 1.02 | 95.9 | ||||
CLR | 8.0 | 4.2 | 0.24 | 36 | 0.93 | 95.4 | ||||
ULR | 2.9 | −6.0 | 0.38 | 28 | 0.97 | 95.2 | ||||
B | Intensity | 1.39 | WC1 | 2.9 | 3.0 | 0.63 | 160 | 0.88 | 90.4 | |
WC2 | - | - | - | - | 1.18 | 98.8 | ||||
CLR | 4.6 | 4.6 | 0.15 | 326 | 0.92 | 95.9 | ||||
ULR | −2.8 | −2.7 | 0.36 | 208 | 1.02 | 93.7 | ||||
Duration | 0.05 | WC1 | −0.7 | 1.1 | 0.44 | 23 | 0.79 | 86.9 | ||
WC2 | - | - | - | - | 1.04 | 95.9 | ||||
CLR | −1.8 | 0.6 | 0.24 | 31 | 0.94 | 95.4 | ||||
ULR | −7.7 | −6.2 | 0.39 | 25 | 0.98 | 94.5 | ||||
Time since cessation | 0.04 | WC1 | −1.2 | 11.2 | 0.46 | 26 | 0.82 | 88.7 | ||
WC2 | - | - | - | - | 1.07 | 95.4 | ||||
CLR | −0.3 | 9.5 | 0.25 | 35 | 0.97 | 95.6 | ||||
ULR | −2.3 | −13.2 | 0.40 | 27 | 1.01 | 95.6 |