Table 6 Simulation results in a domain with ICC = 5%, Pearson correlation X1 and random effect 0.0, number of patients 1000, number of centers 50
From: Prediction models for clustered data: comparison of a random intercept and standard regression model
Apparent performance | Test performance | ||||
|---|---|---|---|---|---|
Standard model | Marginal risk calculation | Conditional risk calculation | Standard model | Marginal risk calculation | |
Harrell’s C-index † | 0.79 (0.762; 0.819) | 0.79 (0.762; 0.819) | 0.82 (0.787; 0.847) | 0.78 (0.779; 0.785) | 0.78 (0.779; 0.785) |
C-index within clusters ‡ | 0.80 (0.123) | 0.80 (0.123) | 0.80 (0.123) | 0.79 (0.031) | 0.79 (0.031) |
Calibration intercept* | 0.00 | 0.03 | 0.01 | -0.01 | 0.03 |
Calibration intercept* within clusters ‡ | -0.03 (0.455) | -0.00 (0.468) | 0.01 (0.000) | -0.03 (0.492) | 0.00 (0.501) |
Calibration slope (overall) | 1.00 | 0.96 | 1.09 | 0.96 | 0.92 |
Calibration slope within clusters ‡ | 1.05 (0.095) | 1.00 (0.096) | 1.10 (0.000) | 1.00 (0.027) | 0.96 (0.026) |