Figure 2

Presents the posterior distributions of the between-trial variance parameters in the first illustrative example under the six employed MTC models: the homogeneous variance model (row 1); the unrestricted variances model (row 2); the exchangeable variances model (row 3); the consistency variances model (row 4); the frequentistically informed variances model (row 5); and the empirically informed variances model (row 6). The two presented comparisons are: peginterferon-2a (PEG-2A) vs Interferon (INF) (column 1), and Peginterferon-2a (PEG-2A) vs Peginterferon-2b (PEG-2B) (column 2). The comparison of PEG-2B vs INF was selective excluded due to the posterior variance distributions being more similar across the five heterogeneous variance approaches.