Assessment of reproducibility of cancer survival risk predictions across medical centers

Table 6 Estimates of correlation between predicted risk scores from a center’s own training model and predicted risk scores using the training model of another center (training center) are given in the first three rows of each table (model transferability)

Center	Training Center	A	B	C	D	E	F	G	H
UM	HLM	0.74	0.62	0.56	0.33	0.58	0.43	0.56	0.42
	DFCI	0.77	0.56	0.56	0.14	0.71	0.32	0.65	0.27
	MSK	0.66	0.47	0.41	0.25	0.49	0.34	0.47	0.31
	HLM and DFCI	0.83	0.78	0.54	0.19	0.46	0.4	0.59	0.39
	HLM and MSK	0.58	0.38	0.39	0.22	0.34	0.23	0.33	0.18
	DFCI and MSK	0.5	0.36	0.2	0	0.3	0.11	0.35	0.15
HLM	UM	0.65	0.63	0.49	0.09	0.63	0.25	0.53	0.27
	DFCI	0.83	0.77	0.5	0.21	0.53	0.34	0.64	0.37
	MSK	0.53	0.18	0.27	0.37	0.38	0.4	0.28	0.33
	UM and DFCI	0.68	0.66	0.5	0.25	0.75	0.47	0.65	0.47
	UM and MSK	0.72	0.46	0.34	0.12	0.54	0.29	0.54	0.2
	DFCI and MSK	0.44	0.27	0.2	0.03	0.47	0.24	0.49	0.19
DFCI	UM	0.84	0.62	0.6	0.29	0.72	0.54	0.65	0.43
	HLM	0.86	0.87	0.53	0.35	0.56	0.43	0.67	0.48
	MSK	0.56	0.41	0.19	0.34	0.23	0.38	0.31	0.36
	UM and HLM	0.72	0.62	0.52	0.37	0.61	0.55	0.6	0.51
	UM and MSK	0.7	0.54	0.44	0.34	0.51	0.38	0.51	0.28
	HLM and MSK	0.61	0.34	0.41	0.27	0.38	0.28	0.3	0.17
MSK	UM	0.7	0.5	0.35	0.35	0.45	0.46	0.46	0.36
	HLM	0.66	0.19	0.5	0.39	0.45	0.3	0.32	0.29
	DFCI	0.54	0.21	0.41	0.06	0.32	0.11	0.41	0.11
	UM and HLM	0.75	0.55	0.42	0.14	0.55	0.32	0.47	0.27
	UM and DFCI	0.76	0.52	0.7	0.35	0.71	0.42	0.6	0.39
	HLM and DFCI	0.88	0.77	0.59	0.28	0.48	0.52	0.62	0.49

The last three rows (consistency) display the correlation between predicted risk scores of the “center” using the training models developed by the “training centers.”

ISSN: 1471-2288