Table 3 The use of systematic reviews in trial design
Area of use | Number of applications (%) |
|---|---|
| Â | (n=37) |
Justification of treatment comparisons | 6 (16.2) |
Choice of frequency/dose | 2 (5.4) |
Selection or definition of outcome | 7 (18.9) |
Recruitment and consent | 2 (5.4) |
Estimating the difference to detect or margin of equivalence | 6 (16.2) |
Estimating the control group event rate | 3 (8.1) |
Inform standard deviation | 1 (2.7) |
Duration of follow up | 8 (21.6) |
Withdrawal rate | 1 (2.7) |
Adverse events | 9 (24.3) |