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Table 3 Results from four multinomial logistic regression analyses

From: Shape information from glucose curves: Functional data analysis compared with traditional summary measures

  Model 1: FPC1, FPC2 and FPC3 scores, gestational weeks 14–16*
2-h value, gestational weeks 30-32 n FPC1 scoresa FPC2 scores FPC3 scores
   Mean (SD) OR (95% CI) p p b Mean (SD) OR (95% CI) p p b Mean (SD) OR (95% CI) p p b
≥8.84 19 12.6 (13.5) 1.08 (1.04,1.13) <0.001 0.40 5.7 (5.1) 1.36 (1.20,1.53) <0.001 0.01 −0.7 (3.0) 0.87 (0.68,1.10) 0.23 0.05
[7.8,8.84) 32 11.1 (13.1) 1.11 (1.07,1.14) <0.001 0.59 1.8 (4.7) 1.14 (1.04,1.25) 0.01 0.02 0.5 (1.6) 1.14 (0.95,1.37) 0.16 0.41
[6.90,7.8) 83 9.4 (12.8) 1.10 (1.07,1.12) <0.001 0.02 −0.1 (3.1) 1.01 (0.95,1.08) 0.69 0.60 0.2 (1.9) 1.05 (0.93,1.19) 0.47 0.57
[6.39,6.90) 94 4.9 (9.6) 1.06 (1.04,1.09) <0.001   −0.5 (3.8) 0.99 (0.93,1.06) 0.79   0.1 (1.8) 1.00 (0.89,1.13) 0.98  
[3.89,6.39) 601 −1.8 (9.7) 1 Ref   −0.2 (3.4) 1 Ref   0.1 (1.8) 1 Ref  
[3.27,3.89) 70 −6.9 (8.7) 0.94 (0.91,0.98) <0.001 <0.01 0.0 (3.0) 0.98 (0.90,1.06) 0.62 0.07 −0.5 (1.7) 0.85 (0.74,0.98) 0.03 0.63
<3.27 23 −12.0 (9.8) 0.83 (0.78,0.90) <0.001   −0.9 (3.8) 0.85 (0.73,0.98) 0.02   −0.8 (2.4) 0.80 (0.62,1.01) 0.07  
   Model 2: Fasting value gestational weeks 14-16* Model 3: 2-h value gestational weeks 14-16* Model 5: Simple shape index c gestational weeks 14-16*
   Mean (SD) OR (95% CI) p p b Mean (SD) OR (95% CI) p p b Mean (SD) OR (95% CI) p p b
≥8.84 19 4.1 (0.5) 2.00 (0.57,6.86) 0.28 0.55 5.5 (1.4) 3.40 (2.24,5.18) <0.001 0.71 −0.80 (1.3) 0.53 (0.30,0.92) 0.03 0.36
[7.8,8.84) 32 4.1 (0.3) 3.17 (1.22,8.01) 0.02 0.54 5.3 (1.4) 3.11 (2.24,4.33) <0.001 0.07 −0.47 (0.8) 0.73 (0.46,1.17) 0.19 0.92
[6.90,7.8) 83 4.2 (0.4) 4.43 (2.26,7.71) <0.001 0.03 4.9 (1.1) 2.25 (1.79,2.84) <0.001 0.01 −0.47 (0.8) 0.71 (0.52,0.97) 0.03 0.84
[6.39,6.90) 94 4.1 (0.4) 1.87 (0.99,3.25) 0.04   4.4 (0.9) 1.58 (1.26,1.98) <0.001   −0.51 (0.7) 0.74 (0.55,1.00) 0.05  
[3.89,6.39) 601 4.0 (0.4) 1 Ref   4.0 (0.9) 1 Ref   −0.29 (0.7) 1 Ref  
[3.27,3.89) 70 3.8 (0.3) 0.32 (0.15,0.65) <0.01 0.63 3.5 (0.8) 0.57 (0.42,0.78) <0.001 <0.01 −0.28 (0.7) 0.95 (0.66,1.37) 0.80 0.18
<3.27 23 3.8 (0.4) 0.23 (0.09,0.93) 0.01   2.9 (0.4) 0.24 (0.14,0.41) <0.001   −0.33 (1.1) 0.60 (0.34,1.07) 0.09  
  1. a The FPC1 scores in model 1 and the AUC in model 4 yielded nearly identical results and the AUC results are thus not shown.
  2. b p values from pairwise comparison between adjacent groups.
  3. c n=711. Calculated as 2-h value minus 90-min value, or 90-min minus 60-min value [12].
  4. * Categories of 2-h values in the third trimester is the response variable and OGTT characteristics in gestational weeks 14–16 are explanatory variables. All models are adjusted for BMI in gestational weeks 14–16.