|
AALL02P2
|
T
|
≥10 (or)*
|
≥50 (or)
| | |
HR
|
|
AALL0031
| | | |
t(9;22) or hypodiploidy or MLL with slow response (or)
|
Induction failure (or)
|
HR
|
|
AALL0232
|
B
|
≥10 (or)
|
≥50 (or)
| |
Steroid pre treatment (or)
|
HR
|
|
AALL0331
|
B
|
1-9
|
<50
| | |
SR
|
|
AALL0434
|
T
|
>1
| | | |
HR
|
|
AALL0622
| |
>1
| |
t(9;22)
| |
HR
|
|
AALL0631
| |
<1
| | | |
HR
|
|
AALL0932
|
B
|
1-9
|
<50
|
No t(9;22), MLL, iAMP21, hypodiploidy
| |
SR
|
|
CCG1991
|
B
|
1-9
|
<50
| | |
SR
|
|
POG9201
|
B
|
1-9
|
<50
|
Trisomy 4,10, DI>1.16 or t(12;21); No t(9;22), 1;19, MLL
| |
SR
|
|
POG9407
| |
<1
| | | |
HR
|
|
POG9605
|
B
|
1-9
|
<50
|
No trisomy 4,10, DI>1.16, MLL, t(1;19), t(9;22)
| |
SR
|
| |
B
|
≥10
|
<50
|
Trisomy 4,10 or DI>1.16; No MLL, t(1;19), t(9;22)
| |
SR
|
| |
B
|
>1
|
≥50
|
Trisomy 4,10 or DI>1.16; No MLL, t(1;19), t(9;22)
| |
SR
|
|
POG9904
|
B
|
1-9
|
<50
|
Trisomy 4,10, DI>1.16 or t(12;21); No MLL, t(1;19), t(9;22)
| |
SR
|
|
POG9905
| | | | |
Neither 9904, 9906 nor AALL0031
|
SR
|
|
POG9906
|
B
|
M>12; F>16 (or)
|
>100 (or)
|
MLL (or)
| |
HR
|
| |
B
|
Sliding scale of WBC criteria for M age 8–11 and F age 12-15
| |
HR
|
|
Protocol C
| |
<1 or >10 (or)
|
>20 (or)
|
t(9;22) or MLL (or)
|
L2 morphology, mediastinal mass, or massive LN/HSM
|
HR
|
