Table 6 Sub-group analysis of item responses by Study Size (in quartiles)
From: Risk of bias of randomized controlled trials published in orthopaedic journals
Randomization | Y | N | DK |
|---|---|---|---|
Size < 51 | 35(61.4) | 5(8.8) | 17(29.8) |
51 ≤ size < 81 | 41(70.7) | 5(8.6) | 12(20.7) |
81 ≤ size < 158 | 53(84.1) | 3(4.8) | 7(11.1) |
Size ≥ 158 | 36(59.0) | 4(6.6) | 21(34.4) |
Allocation Concealment | |||
Size < 51 | 33(57.9) | 4(7.0) | 20(35.1) |
51 ≤ size < 81 | 42(72.4) | 5(8.6) | 11(19.0) |
81 ≤ size < 158 | 52(82.5) | 3(4.8) | 8(12.7) |
Size ≥ 158 | 37(60.7) | 3(4.9) | 21(34.4) |
Blinding of Participants | |||
Size < 51 | 9(15.8) | 10(17.5) | 38(66.7) |
51 ≤ size < 81 | 9(15.5) | 10(17.2) | 39(67.2) |
81 ≤ size < 158 | 15(23.8) | 19(30.2) | 29(46.0) |
Size ≥ 158 | 16(26.2) | 12(19.7) | 32(54.1) |
Blinding of Assessors | |||
Size < 51 | 25(43.9) | 7(12.3) | 25(43.9) |
51 ≤ size < 81 | 30(51.7) | 10(17.2) | 18(31.0) |
81 ≤ size < 158 | 34(54.0) | 9(14.3) | 20(31.8) |
Size ≥ 158 | 29(47.5) | 12(19.7) | 20(32.8) |
Outcome Measurement | |||
Size < 51 | 54(94.7) | 1(1.8) | 2(3.5) |
51 ≤ size < 81 | 54(93.1) | 1(1.7) | 3(5.2) |
81 ≤ size < 158 | 61(96.8) | 0(0) | 2(3.2) |
Size ≥ 158 | 56(91.8) | 0(0) | 5(8.2) |
Similarly Trained Individuals | |||
Size < 51 | 29(50.9) | 1(1.8) | 27(47.4) |
51 ≤ size < 81 | 38(65.5) | 0(0) | 20(34.5) |
81 ≤ size < 158 | 31(49.2) | 2(3.2) | 30(47.6) |
Size ≥ 158 | 15(24.6) | 0(0) | 46(75.4) |
Compliance with Intervention | |||
Size < 51 | 28(49.1) | 29(5.9) | 0(0) |
51 ≤ size < 81 | 39(67.2) | 18(31.0) | 1(1.7) |
81 ≤ size < 158 | 53(84.1) | 10(15.9) | 0(0) |
Size ≥ 158 | 46(75.4) | 15(24.6) | 0(0) |
Intent to Treat Analysis | |||
Size < 51 | 10(17.5) | 0(0) | 47(82.5) |
51 ≤ size < 81 | 15(25.9) | 0(0) | 43(74.1) |
81 ≤ size < 158 | 39(61.9) | 1(1.6) | 23(36.5) |
Size ≥ 158 | 39(63.9) | 3(4.9) | 19(31.1) |
Clustering | |||
Size < 51 | 0(0) | 0(0) | 57(100) |
51 ≤ size < 81 | 0(0) | 0(0) | 58(100) |
81 ≤ size < 158 | 1(1.6) | 0(0) | 62(98.4) |
Size ≥ 158 | 0(0) | 0(0) | 61(100) |
Similar at Baseline | |||
Size < 51 | 37(64.9) | 2(3.5) | 18(31.6) |
51 ≤ size < 81 | 39(67.2) | 3(5.2) | 16(27.6) |
81 ≤ size < 158 | 47(74.6) | 7(11.1) | 9(14.3) |
Size ≥ 158 | 45(73.8) | 8(13.1) | 8(13.1) |