Abstract | ClinicalTrials.gov | |
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1 | 1. lutein, zeaxanthin and long chain polyunsaturated fatty acids (LCPUFAs) | 1. lutein, zeaxanthin, and 3 omega polyunsaturated fatty acid (PUFA) |
2. lutein and zeaxanthin | 2. placebo for 3 omega (PUFA) | |
3. LCPUFAs, docosahexanoic acid, and eicosapentanoic acid | 3. placebo for lutein, zeaxanthin and 3 omega PUFA | |
4. 4 mg triamcinolone | ||
5. 1 mg triamcinolone | ||
6. standard of care | ||
2 | 1. 0.5D lens, head fixed | 1. spectacle lenses |
2. 0.5D lens, head free | 2. different spectacle lenses | |
3. 1.0D lens, head fixed | ||
4. 1.0D lens, head free | ||
5. plano lens, head fixed | ||
6. plano lens, head free | ||
3 | 1. folic acid, vitamin B6 and vitamin B12 | 1. aspirin ± vitamin E |
2. placebo | 2. vitamin E ± vitamin C | |
3. vitamin E ± vitamin C ± beta carotene ± folate | ||
4. placebo | ||
4 | 1. photocoagulation using ETDRS grid | 1. 810 nm diode laser photocoagulation |
2. photocoagulation with normal micro-pulsed technique | 2. argon laser photocoagulation | |
3. photocoagulation with high density micro-pulsed technique | ||
5 | 1. 0.3 mg ranibizumab monthly for 6 months | 1. treatment with ranibizumab until resolution of macular edema or as macular edema occurs |
2. 0.5 mg ranibizumab monthly for 6 months | 2. treatment with ranibizumab until resolution of edema and pigment epithelial detachment or as macular edema or pigment epithelial detachment occur | |
3. 3 doses of ranibizumab, then treatment until macular fluid or pigment epithelial detachment absent | ||
6 | 1. laser photocoagulation | 1. early treatment |
2. conventional treatment | 2. standard of care | |
7 | 1. SofFlex IOL | 1. Acrysof Natural lens |
2. SofPort IOL | 2. AmoSensar Lens | |
8 | 1. plano lens plus weekend atropine | 1. patching plus near activities at least one hour per day |
2. weekend atropine | 2. atropine plus near activities at least one hour per day | |
3. full spectacle correction plus weekend atropine | ||
4. 2 hours daily patching | ||
9 | 1. contact lens care system with polyquaternium-1 and MAPD | 1. silicone hydrogel contact lens |
2. contact lens care system with PHMB | 2. 1XPMBH preserved MPS | |
3. 1XPolyguad/Aldox MPS |