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Table 3 Simulation results demonstrating the application of the DeLong et al. method [[3]] and the U-statistics based method [[9]] for comparing two fixed models under the null hypothesis

From: On the assessment of the added value of new predictive biomarkers

   N 0=50N 1=50 N 0=50N 1=100 N 0=100N 1=200
ρ=0 μ=0 0.0531/0.0547 0.0501/0.0507 0.0515/0.0521
  μ=1 0.0515/0.0527 0.0542/0.0558 0.0503/0.0511
  μ=1.5 0.0482/0.0498 0.0503/0.0512 0.0496/0.0500
ρ=0.6 μ=0 0.0507/0.0530 0.0488/0.0505 0.0515/0.0526
  μ=1 0.0457/0.0493 0.0501/0.0519 0.0485/0.0500
  μ=1.5 0.0453/0.0486 0.0444/0.0471 0.0501/0.0517
  1. Fraction of significant findings in 20,000 Monte Carlo trials at statistical significance cut-off of 0.05 for the DeLong et al. method and the U-statistics based method respectively.