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Table 2 Sensitivity, specificity, and positive predictive value (PPV) of three claims-based measures defined concurrently with diagnosis of prostate cancer

From: Concordance between administrative claims and registry data for identifying metastasis to the bone: an exploratory analysis in prostate cancer

  Claims-based measure of BM-related utilization concurrent with diagnosis
  Approach 1 Approach 2 Approach 3
Sensitivity (95% CI*) 0.598 (0.574 - 0.621) 0.555 (0.531 - 0.579) 0.480 (0.456 - 0.504)
Specificity (95% CI*) 0.538 (0.507 - 0.569) 0.584 (0.553 - 0.614) 0.620 (0.590 - 0.650)
PPV (95% CI*) 0.684 (0.660 - 0.708) 0.690 (0.665 - 0.715) 0.679 (0.651 - 0.705)
  1. *95% confidence intervals were calculated using the Clinical research calculator from VassarStats[18] based on: Newcombe, Robert G. “Two-Sided Confidence Intervals for the Single Proportion: Comparison of Seven Methods”, Statistics in Medicine, 17, 857–872 (1998).