BMC Medical Research Methodology

Table 1 Generated parameter sets for both scenarios

From: Accuracy of the Berger-Exner test for detecting third-order selection bias in randomised controlled trials: a simulation-based investigation

PSN	RM	N	TF/n	PSN	RM	N	TF/n
01	Fixed/BS = 4	120	10/12	33	Varying	240	50/120
02			20/24	34		480	10/48
03			50/60	35			20/96
04		240	10/24	36			50/240
05			20/48	37	Maximal procedure/MTI = 2	120	10/12
06			50/120	38			20/24
07		480	10/48	39			50/60
08			20/96	40		240	10/24
09			50/240	41			20/48
10	Fixed/BS = 6	120	10/12	42			50/120
11			20/24	43		480	10/48
12			50/60	44			20/96
13		240	10/24	45			50/240
14			20/48	46	Maximal procedure/MTI = 3	120	10/12
15			50/120	47			20/24
16		480	10/48	48			50/60
17			20/96	49		240	10/24
18			50/240	50			20/48
19	Fixed/BS = 8	120	10/12	51			50/120
20			20/24	52		480	10/48
21			50/60	53			20/96
22		240	10/24	54			50/240
23			20/48	55	Maximal procedure/MTI = 4	120	10/12
24			50/120	56			20/24
25		480	10/48	57			50/60
26			20/96	58		240	10/24
27			50/240	59			20/48
28	Varying	120	10/12	60			50/120
29			20/24	61		480	10/48
30			50/60	62			20/96
31		240	10/24	63			50/240
32			20/48

PSN = Parameter set number; RM = Randomisation method; TF = Trait frequency; N = Subject number; n = Number of subjects per TF; BS = Block size; MTI = Maximum tolerated imbalance; Fixed = Fixed block randomisation.
Varying = Block randomisation with randomly varying block size 4, 6, 8 with equal probability (1/3).

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ISSN: 1471-2288

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