Model | TGLMM | Model 1 | Model2 | Model3 | Intent-to-diagnose | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estimate | Bias% | meanSE | CP | Bias% | meanSE | CP | Bias% | meanSE | CP | Bias% | meanSE | CP | Bias% | meanSE | CP |
ω m1 =ω m0 =0.1 | |||||||||||||||
Se | −0.3 | 0.041 | 0.94 | −0.3 | 0.041 | 0.94 | 4.6 | 0.036 | 0.81 | −12.6 | 0.037 | 0.33 | −12.6 | 0.036 | 0.33 |
Sp | −0.1 | 0.017 | 0.93 | −0.1 | 0.017 | 0.93 | −11.9 | 0.018 | 0 | 1.1 | 0.015 | 0.84 | −11.9 | 0.017 | 0 |
Prev | 0.8 | 0.034 | 0.93 | 0.8 | 0.034 | 0.93 | 0.8 | 0.034 | 0.93 | 0.8 | 0.034 | 0.93 | 0.8 | 0.034 | 0.93 |
PPV | −0.1 | 0.046 | 0.94 | −0.3 | 0.046 | 0.94 | −22.6 | 0.047 | 0.08 | −0.9 | 0.046 | 0.94 | −29 | 0.049 | 0.01 |
NPV | −0.1 | 0.018 | 0.93 | −0.1 | 0.018 | 0.93 | −0.2 | 0.018 | 0.93 | −2.9 | 0.020 | 0.81 | −4.6 | 0.022 | 0.59 |
LR+ | 1.6 | 1.188 | 0.92 | 1.6 | 1.189 | 0.93 | −49.2 | 0.307 | 0 | −0.5 | 1.160 | 0.92 | −57.6 | 0.271 | 0 |
LR − | 0.9 | 0.044 | 0.94 | 0.9 | 0.044 | 0.94 | 1.5 | 0.044 | 0.94 | 27.9 | 0.039 | 0.33 | 46.8 | 0.045 | 0.04 |
ω m1 =0.1,ω m0 =0.2 | |||||||||||||||
Se | −0.1 | 0.041 | 0.94 | −0.1 | 0.041 | 0.94 | 4.7 | 0.036 | 0.80 | −12.3 | 0.036 | 0.34 | −12.3 0.036 | 0.34 | |
Sp | −0.1 | 0.017 | 0.94 | −0.1 | 0.017 | 0.94 | −22.3 | 0.017 | 0 | 2.2 | 0.014 | 0.62 | −22.3 | 0.017 | 0 |
Prev | 0.4 | 0.034 | 0.93 | 9.6 | 0.036 | 0.90 | 0.4 | 0.034 | 0.93 | 0.4 | 0.034 | 0.93 | 0.4 | 0.034 | 0.93 |
PPV | −0.3 | 0.046 | 0.93 | 3.1 | 0.044 | 0.88 | −36 | 0.047 | 0 | 2.7 | 0.044 | 0.89 | −42.1 | 0.047 | 0 |
NPV | −0.1 | 0.018 | 0.94 | −1.3 | 0.020 | 0.93 | −1.4 | 0.020 | 0.92 | −2.7 | 0.020 | 0.83 | −6.3 | 0.024 | 0.36 |
LR+ | 1.4 | 1.195 | 0.94 | 1.4 | 1.194 | 0.94 | −65.1 | 0.159 | 0 | 12.3 | 1.312 | 0.95 | −70.8 | 0.147 | 0 |
LR − | 0.6 | 0.044 | 0.93 | 0.6 | 0.044 | 0.93 | 14.7 | 0.050 | 0.85 | 26.1 | 0.038 | 0.39 | 66.1 | 0.051 | 0 |
ω m1 =0.2,ω m0 =0.1 | |||||||||||||||
Se | -0.1 | 0.023 | 0.93 | -0.1 | 0.023 | 0.93 | 8.7 | 0.018 | 0.12 | -21 | 0.020 | 0 | -21 | 0.019 | 0 |
Sp | 0 | 0.009 | 0.93 | 0 | 0.009 | 0.93 | -10.6 | 0.009 | 0 | 1.1 | 0.008 | 0.74 | -10.6 | 0.009 | 0 |
Prev | 0 | 0.018 | 0.93 | -8.4 | 0.017 | 0.72 | 0 | 0.017 | 0.91 | 0 | 0.017 | 0.91 | 0 | 0.0168 | 0.89 |
PPV | -0.1 | 0.025 | 0.93 | -3.7 | 0.027 | 0.83 | -19.1 | 0.025 | 0 | -4 | 0.026 | 0.8 | -30.6 | 0.025 | 0 |
NPV | 0 | 0.010 | 0.92 | 1.1 | 0.009 | 0.76 | 1.1 | 0.009 | 0.74 | -4.6 | 0.011 | 0.05 | -6.2 | 0.012 | 0 |
LR+ | 0.3 | 0.655 | 0.93 | 0.3 | 0.653 | 0.93 | -44.1 | 0.196 | 0 | -11.7 | 0.570 | 0.62 | -59.3 | 0.154 | 0 |
LR − | 0.3 | 0.025 | 0.93 | 0.3 | 0.025 | 0.93 | -10.8 | 0.022 | 0.62 | 47.4 | 0.021 | 0 | 66.7 | 0.024 | 0 |