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Table 1 Selecting the optimal number of clusters

From: Genomic investigation of etiologic heterogeneity: methodologic challenges

Incremental # sub-types

P-valuesa

mRNA

Methylation

3 vs 2

0.02

<0.01

4 vs 3

0.06

0.04

5 vs 4

0.41

<0.01

  1. aThe p-values determine whether the designated increase in the numbers of clusters leads to significant additional etiological heterogeneity, as described in the text.
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BMC Medical Research Methodology

ISSN: 1471-2288

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