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Table 3 Selected baseline characteristics reported by the included studies

From: Indirect comparisons of ranibizumab and dexamethasone in macular oedema secondary to retinal vein occlusion

Baseline characteristic

GENEVA

BRAVO

CRUISE

 

Sham (n = 426)

Dexamethasone (0.7 mg) (n = 427)

Sham (n = 132)

Ranibizumab (0.5 mg) (n = 131)

Sham (n = 130)

Ranibizumab (0.5 mg) (n = 130)

Mean age (range) (yrs)

63.9 (31–91)

64.7 (33–90)

65.2 (26–89)

67.5 (41–91)

65.4 (20–91)

67.6 (40–91)

Male (%)

56.3

50.8

56.1

54.2

55.4

61.5

Race Caucasian (%)

74.6

75.2

81.8

81.7

86.9

83.1

Mean duration macular oedema* (range)

156.1 (19–374)

157.6 (19–374)

114.7 (0–496)

102.3 (0–403)

89.9 (0–434))

102.3 (0–837)

Mean baseline visual acuitity BCVA (sd)

54.8 (9.86)

54.3 (9.93)

54.7 (12.2)

53.0 (12.5)

49.2 (14.7)

48.1 (14.6)

Mean baseline retinal thickness (SD) (µm)

539 (186)

562 (188)

NR

NR

NR

NR

Fellow eye BCVA (ETDRS letters), mean (SD)

NR

NR

79.8 (17.4)

81.4 (13.8)

78.9 (18.6)

78.8 (17.4)

  1. *In BRAVO and CRUISE studies, this was defined as “Months from RVO diagnosis to screening”. For simplicity of comparison, months are multiplied by 31 to convert to days.